This was a plenary lecture that I gave at the European Society for Organ Transplantation in Glasgow last September 2011. Hopefully some of it is still current and topical!
When you do these talks and pull out what you think are the clinically most relevant papers it is really a challenge. You are required to review pretty much the whole World literature on your subject for a year and decide which articles or stories carry the most impact. Impact can be measured in different ways. Some of the stories I chose were associated with scandal and some were game-changing studies that will alter clinical practice or the way people view a subject. I have also included some carefully designed negative studies which are in some ways equally important because of their quality and certainty in closing a question.
As I said in the disclosure slide this is inevitably subjective and it is quite possible that my opinion of what is important is very different from yours. Oh yes and there was only 15 or 20 minutes to cover quite a lot.